Reframing Immune-Mediated Inflammatory Diseases through Signature Cytokine Hubs

نویسندگان

چکیده

The ability to block specific cytokine pathways has revealed pathophysiological differences among autoimmune diseases (e.g., the efficacy of TNF inhibitors in arthritides and inflammatory bowel disorders their inefficacy giant-cell arteritis multiple sclerosis), providing a framework for reclassification.

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ژورنال

عنوان ژورنال: The New England Journal of Medicine

سال: 2021

ISSN: ['0028-4793', '1533-4406']

DOI: https://doi.org/10.1056/nejmra1909094